EPINET is a national learning health care system that links early psychosis clinics through standard clinical measures, uniform data collection methods and data sharing agreements. The EPINET initiative includes eight regional hubs, 101 early psychosis clinics across 16 states, and the EPINET National Data Coordinating Center (ENDCC). Through this EPINET process and partnership a unique research database will be created and be available to collaborators within and outside of EPINET to support research and improve early psychosis identification and care.